СПИСОК ЛИТЕРАТУРЫ

1 Боровиков, В. П. STATISTICA: искусство анализа данных на компьютере для профессионалов / В.П. Боровиков – Санкт-Петербург: Питер, 2001. – 656 с.

2 Боровиков, В.П. STATISTICA – Статистический анализ и обработка данных в среде Windows / В.П.

608 с.

3 Босак И.А. Сравнительная характеристика природных и клинических изолятов Сryptococcus neoformans: автореф. дисс…канд. мед. наук: 03.00.24 / Босак Илья Алексеевич – СПб., 2009. – 24 с.

4 Босак, И.А. Выделение и характеристика изолятов Cryptococcus neoformans из окружающей среды г. Санкт-Петербурга / И.А. Босак // Проблемы медицинской микологии – 2009. – Т.11, №3. – С. 43-46.

5 Васильева Н.В. Факторы патогенности Cryptococcus neoformans и их роль в патогенезе криптококкоза: дисс…докт. биол. наук: 03.00.24 / Васильева Наталья Всеволодовна – СПб, 2005. – 340 c.

6 ВИЧ-инфекция и центральная нервная система / под ред. Н.А.Белякова, Т.Н.Трофимовой, В.В. Рассохина. Медицинский тематический архив. СПб: Балтийский медицинский образовательный центр, 2013. – 122 с.

7 Елинов, Н.П. Прошлое и настоящее Cryptococcus neoformans (Sanfelice) Vuillemin (1901) как объекта изучения потенциально грозного патогена для человека / Н.П.Елинов, И.А. Босак // Проблемы медицинской микологии. –

2006. –Т.8, №4. – C.47-52.

8 Идентификация клинических изолятов Cryptococcus neoformans методом MALDI-TOF MS / А.А.Ацапкина, И.А. Рябинин, Т.С. Богомолова [и др.] // Проблемы медицинской микологии. − 2014. − Т.16, №2. − С.41.

9 Иммунология / Д. Мейл, Дж. Бростофф, Д.Б. Ройт [и др.] – Москва: Логосфера, 2007. – 568 с.

10 Киселева, Е.П. Метод автоматизированного учета НСТ-теста / Е.П. Киселева, А.В. Полевщиков // Клиническая лабораторная диагностика. – 1994. – №4. – С.27-29.

11 Кокряков, В.Н. Очерки о врожденном иммунитете / В.Н.

12 Микологическое исследование объектов окружающей среды и определение противогрибкововой активности различных веществ: методические рекомендации №2. – СПб. – 2008. – 16 с.

13 Определение видов возбудителей инвазивного кандидоза: в поиске быстрых решений / Е.Р. Рауш, Н.В. Васильева, А.Г. Полищук [и др.] // Проблемы медицинской микологии. – 2013. – Т.15, №4. – С. 87-91.

14 Определение чувствительности возбудителей инвазивного кандидоза к флуконазолу и вориконазолу по международным стандартам / Е.Р. Рауш, И.В. Выборнова, Е.В. Шагдилеева [и др.] // Проблемы медицинской микологии. –

2013. - Т.15, №1. – С. 60-63.

15 Реброва, О.В. Статистический анализ медицинских данных. Применение пакета прикладных программ «Статистика» / О.В. Реброва – 3-е изд. – Москва: Медиа Сфера, 2006. – 312 с.

16 Роль патогенных и условно-патогенных грибов в жизни человека: учебное пособие, выпуск II. / А.Д. Юцковский, Н.В. Васильева, Л.М. Кулагина [и др.] (под ред. Елинова Н.П.) // СПб.: Политехника-сервис, 2014. – 206 с.

17 Руководство по лабораторным животным и альтернативным моделям в биомедицинских исследованиях: учебное пособие для системы медицинского и фармацевтического послевузовского образования / под ред.: Н. Н. Каркищенко, С. В. Грачев. - М.: Профиль, 2010. - 358 с.

18 Трухачева, Н.В. Математическая статистика в медико-биологических исследованиях с применением пакета STATISTICA / Н.В. Трухачева – Москва: ГЭОТАР-Медиа, 2012. – 384 с.: ил.

19 Хаитов, Р.М. Иммунология: атлас / Р.М. Хаитов, А.А.Ярилин, Б.В. Пинегин – М.: ГЭОТАР-Медиа, 2011. – 624 с.: ил.

20 A case of fluconazole, voriconazole-resistant Cryptococcus neoformans isolated from an immunocompetent patient / N. Mandras, J Roana, V Tullio [et al.] // J Chemother. –2011.–Vol. 23, № 6. – P. 379-380.

21 A chitin synthase and its regulator protein are critical for chitosan production and growth of the fungal pathogen Cryptococcus neoformans / I.R. Banks, C.A. Specht, M.J.

22 A differential effect of Cryptococcus neoformans on the production of IL-12p40 and IL-10 by murine macrophages stimulated with lipopolysaccharide and gamma interferon / K. Kawakami, M.H. Qureshi, Y. Koguchi et al. // FEMS Microbiology Letters. – 1999. – Vol.175. – P. 87-94.

23 A distinct role for interleukin-13 in Th2-cell-mediated immune responses / G.J.

McKenzie, A. Bancroft, R.K. Grencis [et al.] // Curr. Biol. – 1998. – Vol. 8. – P.

339-342.

24 A proteomic-based approach for the identification of immunodominant Cryptococcus neoformans proteins / M. Young, S. Macias, D. Thomas [et al.] // Proteomics. – 2009. – Vol. 9. – P. 2578-2588.

25 A rare genotype of Cryptococcus gattii caused the cryptococcosis outbreak on Vancouver Island (British Columbia, Canada) / S.E. Kidd, F. Hagen, R.L. Tscharke [et al.] // Proc. Natl. Acad. Sci. USA. – 2004. – Vol. 101. – P. 17258-17263.

26 A survey of heterobasidiomycetous yeasts for the presence of the genes homologous to virulence factors of Filobasidiella neoformans, CNLAC1 and CAP59 / R. Petter, B.S. Kang, T. Boekhout [et al.] // Microbiology. – 2001. – Vol.

147. – P. 2029-2036.

27 A yeast under cover: the capsule of Cryptococcus neoformans / I. Bose, A.J. Reese, J.J. Cry [et al.] // Eukaryotic Cell. – 2003. –Vol. 2. – N 4. – P. 655-663.

28 Aguirre, K.M., Gibson G.W. Differing requirement for inducible nitric oxide synthase activity in clearance of primary and secondary Cryptococcus neoformans infection / K.M. Aguirre, G.W.Gibson // Med. Mycol. – 2000. – Vol. 38. – P. 343-

353.

29 Alanio, A. Dynamics of Cryptococcus neoformans - macrophage interactions reveal that fungal background influences outcome during Cryptococcal meningoencephalitis in humans [Electronic resource] / A. Alanio, M. Desnos- Ollivier, F. Dromera. – Mode of access: http: //mbio.asm.org/content/2/4/e00158-

11.

30 Alspaugh, J.A. Signal transduction pathways regulating differentiation and pathogenicity of Cryptococcus neoformans / J.A.

31 An innate immune system cell is a major determinant of species-related susceptibility differences to fungal pneumonia / X. Shao, A. Mednick, M. Alvarez [et al.] // J. Immunol. – 2005. – Vol. 175. – P. 3244-3251.

32 An integrated model of the recognition of Candida albicans by the innate immune system / M.G. Netea, G.D. Brown, B.J. Kullberg [et al.] // Nat. Rev. Microbiol. –

2008. – Vol. 6, № 1. – P. 67-78.

33 Analysis of human monoclonal antibodies elicited by vaccination with a

Cryptococcus neoformans glucuronoxylomannan capsular polysaccharide vaccine

/L. Pirofski, R. Lui, M. DeShaw [et al.] // Infect. Immun. – 1995. – Vol. 63, № 8. –

P. 3005-3014.

34 Antibody interactions with the capsule of Cryptococcus neoformans / M.

Feldmesser, J. Rivera, Y. Kress [et al.] // Infect. Immun. – 2000. – Vol. 68, № 6. –

P. 3642-3650.

35 Anti-fungal activity of cathelicidins and their potential role in Candida albicans skin infection / B. Lopez-Garcia, P.H. Lee, K. Yamasaki [et al.] // J. Investig. Dermatol. – 2005. – Vol. 125. – P. 108-115.

36 Anti-inflammatory and immunomodulating properties of grape melanin. Inhibitory effects on paw edema and adjuvant induced disease / N. Arramidis, A. Kourounahis, L. Hadjipetrou [et al.] // Arzneimittelforschung. – 1998. – Vol. 48. – P. 764-771.

37 App1: An antiphagocytic protein that binds to complement receptors 3 and 2 / P.

Stano, V. Williams, M. Villani [et al.] // Journal of Immunology. – 2009. – Vol.

182 – P. 84–91.

38 Arginase and polyamine synthesis are key factors in the regulation of experimental leishmaniasis in vivo / P. Kropf, J.M. Fuentes, E. Fahnrich [et al.] // FASEB J. –

2005. – Vol. 19. – P. 1000-1002.

39 Atlas of clinical fungi: electronic version 3.1. [Electronic resource] / Hoog G.S. de, Guarro J., Gene J. [et al.].- Utrecht, Reus, 2011. – (СD-ROM).

40 Baddley, J.W. Pulmonary cryptococcosis in patients without HIV infection: factors associated with disseminated disease / J.W.

41 Barluzzi, R. Establishment of protective immunity against cerebral cryptococcosis by means of an avirulent non melanogenic Cryptococcus neoformans strain / R. Barluzzi, A. Brozetti, G. Mariucci // J. Neuroimmunol. – 2000. – Vol. 109. – P. 75-

86.

42 Bartlett, K.H. The emergence of Cryptococcus gattii in British Columbia and the Pacific Northwest / K.H. Bartlett, S.E. Kidd, J.W. Kronstad // Curr. Infect. Dis. Rep. – 2008. – Vol. 10. – P. 58-65.

43 Bava, A.J. Cryptococcosis produced by a urease negative strain of Cryptococcus neoformans / A.J. Bava, R. Negroni, M. Bianchi // J. Med. Vet. Mycol. – 1993. –

№ 31. – P. 87-89.

44 Blackstock, R. Role of interleukin-4 in resistance to Cryptococcus neoformans infection / R. Blackstock, J.W. Murphy / R. Blackstock // Am. J. Respir. Cell Mol. Biol. – 2004. – Vol. 30. – P.109-117.

45 Blander, J.M. On regulation of phagosome maturation and antigen presentation / J.M. Blander, R. Medzhitov // Nat. Immunol. – 2006. – Vol. 7, №10. – P. 1029-35.

46 Blander, J.M. Toll-depended selection of microbal antigens for presentation by dendritic cells / J.M. Blander, R. Medzhitov // Nature. – 2006. – Vol. 440. – P.

808-812.

47 Brown, A. Nitrosative and oxidative stress responses in fungal pathogenicity A/ Brown, K. Haynes, J. Quinn. // Curr Opin Microbiol. – 2009. – Vol. 12, №4. – P.384-391.

48 Brown, G.D. Innate Antifungal Immunity: the key role of phagocytes / G.D. Brown

// Annu. Rev. Immunol. – 2011. – Vol. 29. – P. 1-21.

49 Bruker Daltonics MALDI-TOF biotyper operation procedure – OP for sample preparation using formic acid extraction method. – 12/15/2010.

50 Buchanan, K.L. Regulation of cytokine production during the expression phase of the anticryptococcal delayed-type hypersensitivity response / K.L. Buchanan, J.W. Murphy // Infect. Immun. – 1994. – P.622930-622939.

51 Buchanan, K.L.

52 Buckland, K.F. Cytokines / K.F. Buckland, C.M. Hogaboam // Immunology of fungal infection / G.D., Brown M.G. Netea (eds.) – Springer, 2007. – P. 201-234.

53 Byrnes, E.J. Cryptococcus gattii outbreak expands into the Northwestern United

States with fatal consequences / E.J. Byrnes, J. Heitman // F1000 Biol. Reports . –

2009c. – Vol.1. – pii: 62.

54 Campbell, G.D. Primary pulmonary cryptococcosis / G.D. Campbell // Am. Rev.

Respir. Dis. – 1966. – Vol. 94. – P. 236-243.

55 Capsular polysaccharide of Cryptococcus neoformans induces proinflammatory cytokine release by human neutrophils / C. Retini, A. Vecchiarelli, C. Monari [et al.] // Infect. Immun. – Vol. 64 – P. 2897-2903.

56 Capsular polysaccharides galactoxylomannan and glucuronoxylomannan from Cryptococcus neoformans induce macrophage apoptosis mediated by Fas ligand / S.N. Villena, R.O. Pinheiro, C.S. Pinheiro [et al.] // Cell. Microbiol. – 2008. – Vol.

10, № 6. – P. 1274-1285.

57 Capsule of Cryptococcus neoformans grows by enlargement of polysaccharide molecules / S. Frases, B. Pontes, L. Nimrichter [et al.] // Proc. Natl. Acad. Sci. USA. – 2009. – Vol. 106, № 4. – P. 1228-1233.

58 Casadevall, A. Cryptococcus neoformans / A. Casadevall, J. Perfect // ASM Press.,

1998.

59 Casadevall, A. Melanin and virulence in Cryptococcus neoformans / A. Casadevall, A.L. Rosas, J.D. Nosanchuk // Curr. Opin. Microbiol. – 2000. – Vol. 3. – P. 354-

358.

60 Casadevall, A. Virulence factors and their mechanisms of action: the view from a damage-response framework: Review / Casadevall A., Pirofski L.A. // J. Water Health. – 2009. – Vol. 7, Suppl. 1. – S2-S18.

61 Characterization of anticapsular monoclonal antibodies that regulate activation of the complement system by the Cryptococcus neoformans capsule / T.R. Kozel, B.C.H. DeJong, M.M. Grinsell [et al.] // Infect. Immun. – 1998. – Vol. 66, № 4. – P. 1538-1546.

62 Chemical nature of an uronic acid-containing polysaccharide in the peritrophic membrane of the silkworm / K. Nisizawa, T. Yamaguchi, N. Handa [et al.] // J. Biochem. – 1963. – Vol.54. – P 419 - 426.

63 Chitin induces accumulation in tissue of innate immune cells associated with allergy / T.A. Reese, H.E. Liang, A.M Tager [et al.] // Nature. – 2007. – Vol. 447.

– P. 92-96.

64 Chomarat, P. Interleukin-4 and interleukin-13: their similarities and discrepancies / P. Chomarat, J. Banchereau // Int. Rev. Immunol. – 1998. – Vol. 17. – P. 1-52.

65 Chronological aging is associated with biophysical and chemical changes in the capsule of Cryptococcus neoformans / R.J. Cordero, B. Pontes, A. J. Guimaraes [et al.] // Infection and Immunity. – 2011. – Vol.79. – P. 4990–5000.

66 Clemons, K.V. Cytokine treatment of central nervous system infection: efficacy of interleukin-12 alone and synergy with conventional antifungal therapy in experimental cryptococcosis / K.V. Clemons, E. Brummer, D.A. Stevens // Antimicrob. Agents Chemother. – 1994. – Vol. 38. – P. 460-464.

67 Clinical and Labjratory Standards Institute (CLSI). Reference method for antifungal disk diffusion susceptibility testing of yeasts; approved guideline // CLSI document M44-A. – 2004. – CLSI, Wayne, PA, USA.

68 Coelho, C. The Tools for Virulence of Cryptococcus neoformans / C. Coelho, A. L.

Bocca, A. Casadevall // Advances in Applied Microbiology. – 2014. –Vol. 87 –

P.1-41.

69 Collins, H.L. Cytokine enhancement of complement-dependent phagocytosis by macrophages: synergy of tumor necrosis factor-alpha and granulocyte-macrophage colony-stimulating factor for phagocytosis of Cryptococcus neoformans / H.L. Collins, G. J. Bancroft // Eur. J. Immunol. – 1992. – Vol. 22. – P. 1447-1454.

70 Comparative analysis of pathogenicity of Cryptococcus neoformans serotypes A, D

and AD in murine cryptococcosis / F. Barchiesi, M. Cogliati, M.C. Esposto [et al.]

// J. Infect. – 2005. –Vol. 51, № 1. – P. 10-16.

71 Comparative gene genealogies indicate that two clonal lineages of Cryptococcus gattii in British Columbia resemble strains from other geographical areas / S.E. Kidd, H. Guo, K.H. Bartlett [et al.] // Eukaryot. Cell. – 2005. – Vol. 4, № 10. – P.

1629-1638.

72 Comparative hybridization reveals extensive genome variation in the AIDS- associated pathogen Cryptococcus neoformans / G. Hu, I. Liu, A. Sham [et al.] // Genome Biol. – 2008. – Vol. 9, № 2. – P.41.

73 Consensus multi-locus sequence typing scheme for Cryptococcus neoformans and Cryptococcus gattii / W. Meyer, D.M. Aanensen, T. Boekhout [et al.] // Medical Mycology. – 2009. – Vol. 47. – P. 561-570.

74 Cross, C.E. Ingestion of acapsular Cryptococcus neoformans occurs via mannose and β-glucan receptors, resulting in cytokine production and increased phagocytosis of the encapsulated form / C.E. Cross, G.J. Bancroft // Infect. Immun.

– 1995. – Vol. 63, № 7. – P. 2604-2611.

75 Cryptococcal urease acts as a pulmonary virulence factor by shifting the balance of the adaptive immune response from a protective T1 response towards a non- protective T2 response / R. Surana, G. Montano, S. Arora [et al.] // Abstr. 6th International Conference on Cryptococcus & Cryptococcosis. – Boston, 2005. – P.

147-148.

76 Cryptococcal urease promotes the accumulation of immature dendritic cells and a non-protective T2 immune response within the lung / J.J. Osterholzer, R. Surana, J.E. Milam, [et al.] // Am. J. Pathol. – 2009. – Vol. 174. – P. 932-943.

77 Cryptococcosis in human immunodeficiency virus-negative patients / S.

Kiertiburanakul, S. Wirojtananugoon, R. Pracharktam [et al.] // Int. J. Infect. Dis. –

2006. – Vol. 10, № 1. – P. 72-78.

78 Cryptococcosis in solid organ transplant recipients: current state of the science / N.

Singh, F. Dromer, J.R. Perfect [et al.] // Clin. Infect. Dis. – 2008. – Vol. 47. – P.

1321-1327.

79 Cryptococcuria as a manifestation of disseminated cryptococcosis and isolated urinary tract infection / S. Kiertiburanakul, S. Sungkanuparph, B. Buabut [et al.] // Jpn. J. Infect. Dis. – 2004. – Vol. 57, № 5. – P. 203-205.

80 Cryptococcus gattii dispersal mechanisms, British Columbia, Canada / S.E. Kidd, P.J. Bach, A.O. Hingston [et al.] // Emerg. Infect. Dis. – 2007. – Vol. 13. – P. 51-

57.

81 Cryptococcus gattii induces a cytokine pattern that is distinct from other cryptococcal species [Electronic resource]/ T. Schoffelen, M.-T.Illnait-Zaragozi, L.A.B. Joosten [et al]. – Mode of access: http://www.plosone.org/article/info%3A doi%2F10.1371%2Fjournal.pone.0055579.

82 Cryptococcus neoformans induces macrophage inflammatory protein 1alpha (MIP-

1alpha) and MIP-1beta in human microglia: role of specific antibody and soluble capsular polysaccharide / D. Goldman, X. Song, R. Kitai [et al.] // Infect. Immun. –

2001. – P. 691808-691815.

83 Cryptococcus neoformans inhibits nitric oxide production by murine peritoneal macrophages stimulated with interferon-γ and lipopolysaccharide / K. Kawakami, T. Zhang, M.H. Qureshi [et al.] // Cell. Immunol. – 1997. – Vol.180. – P. 47-54.

84 Cryptococcus neoformans strains and infection in apparently immunocompetent patients, China / J. Chen, A. Varma, M.R. Diaz [et al.] // Emerg. Infect. Dis. –

2008. –Vol. 14, № 5. – P. 755-762.

85 Currie, B.P. Decreased fluconazole susceptibility of a relapse Cryptococcus neoformans isolate after fluconazole treatment / B.P. Currie, M. Ghannoum, L. Bessen [et al.] // Infect. Dis. Clin. Pract. – 1995. – Vol. 4. – P. 318-319.

86 Cytokine and chemokine expression in the central nervous system associated with protective cell-mediated immunity against Cryptococcus neoformans / W.C. Uicker, H.A. Doyle, J.P. McCracken [et al.] // Med. Mycol. – 2005. – Vol. 43. – P.

27-38.

87 Cytokine and inducible nitric oxide synthase mRNA expression during experimental murine cryptococcal meningoencephalitis / C.M.L. Maffei, L.F. Mirels, R.A. Sobel [et al.] // Infect. Immun. – 2004. – Vol. 72. – P. 2338-2349.

88 De Jesus, M. Spleen deposition of Cryptococcus neoformans capsular glucuronoxylomannan in rodents occurs in red pulp macrophages and not marginal zone macrophages expressing the C-type lectin SIGN-R1 / M. De Jesus, C.G. Park, Y. Su // Med. Mycol. – 2008. – Vol.46, № 2. – P.153-162.

89 de Vries, J.E. Receptors and cytokines involved in allergic TH2 cell responses / J.E. de Vries, J.M. Carballido, G. Aversa // J. Allergy Clin. Immunol. – 1999. – Vol. 103. – P. S492–S496.

90 Deciphering the model pathogenic fungus Cryptococcus neoformans / A. Idnurm, Y. S. Bahn, K. Nielsen [et al.] // Nat Rev Microbiol. – 2005. – Vol. 3, № 10. – P.753-764.

91 Dectin-1 is not required for the host defense to Cryptococcus neoformans / K.Nakamura, T. Kinjo, S. Sanjo [et al.] // Microbiol. Immunol. – 2007. – Vol. 51,

№ 11. – P. 1115-1119.

92 Del Poeta, M. Role of phagocytosis in the virulence of Cryptococcus neoformans / M. Del Poeta // Eukaryotic cell. – 2004. – Vol. 3. – P. 1067-1075.

93 Designing antimicrobial peptides: form follows function / C.D. Fjell, J.A. Hiss, R.E.W. Hancock [et al.] // Nat. Reviews. – 2012. − Vol.11. − P. 37-49.

94 Differences between IL-4R alpha-deficient and IL-4-deficient mice reveal a role for IL-13 in the regulation of Th2 responses / M. Barner, M. Mohrs, F. Brombacher [et al.] // Curr. Biol. – 1998. – Vol. 8. – P. 669-672.

95 Differences in outcome of the interaction between Cryptococcus neoformans glucuronoxylomannan and human monocytes and neutrophils / Monari C., Retini C., Casadevall A. [et al.] // Eur. J. Immunol. – 2003. – Vol. 33, № 4. – P. 1041-

1051.

96 Differential regulation of immune responses by highly and weakly virulent Cryptococcus neoformans isolates / R. Blackstock, K.L. Buchanan, A.M. Adesina [et al.] // Infect Immun. – 1999. – Vol. 67. – P. 3601-3609.

97 Differential regulation of nitric oxide synthase-2 and arginase-1 by type 1/type 2 cytokines in vivo: granulomatous pathology is shaped by the pattern of L-arginine metabolism / M. Hesse, M. Modolell, A.C. La Flamme [et al.] // J. Immunol. –

2001. – Vol. 167. – P. 6533-6544.

98 Differential use of CARD9 by dectin-1 in macrophages and dendritic cells / H.S.

Goodridge, T. Shimada, A.J. Wolf [et al.] // J. Immunol. – 2009. – Vol. 182. – P.

1146-1154.

99 Distinct patterns of dendritic cell cytokine release stimulated by fungal β-glucans and Toll-like receptor agonists / H. Huang, G.R. Ostroff, C.K. Lee [et al.] // Infect. Immun. – 2009. – Vol. 77, № 5. – P. 1774-1781.

100 Distinct roles for IL-4 and IL-10 in regulating T2 immunity during allergic bronchopulmonary mycosis / Y. Hernandez, S. Arora, J.R. Erb-Downward [et al.]

// J. Immunol. – 2005. – Vol. 174. – P. 1027-1036.

101 Dong, Z.M. Cryptococcal polysaccharides bind to CD18 on human neutrophils / Z.M. Dong, J.W. Murphy // Infect. Immun. – 1997. – Vol. 65. – P. 557-563.

102 Dong, Z.M. Effects of the two varieties of Cryptococcus neoformans cells and culture filtrate antigens on neutrophil locomotion / Z.M. Dong, J.W. Murphy // Infect. Immun. – 1995. – Vol. 63. – P. 2632-2644.

103 Down-regulation of the afferent phase of T cell-mediated pulmonary inflammation and immunity by a high melanin-producing strain of Cryptococcus neoformans / G.B. Huffnagle, G.H. Chen, J.L. Curtis [et al.] // J. Immunol. – 1995.

– Vol. 155. – P. 3507-3516.

104 Dual role for nitric oxide in paracoccidioidomycosis: essential for resistance, but overproduction associated with susceptibility. / F.R.F. Nascimento, V.L.G. Calich, D. Rodriguez [et al.] // J Immunol. – 2002. – Vol. 168. – P. 4593-4600.

105 Early cytokine production in pulmonary Cryptococcus neoformans infections distinguishes susceptible and resistant mice / K.A. Hoag, N.E. Street, G.B. Huffnagle [et al.] // Am. J. Respir. Cell Mol. Biol. – 1995. – Vol. 13. – P. 487-495.

106 Effects of melanin upon susceptibility of Cryptococcus to antifungals / R. Ikeda, T. Sugita, E.S. Jacobson [et al.] // Microbiol. Immunol. – 2003. – Vol. 47. – P. 271-

277.

107 Effects of the capsular polysaccharides of Cryptococcus neoformans on phagocyte migration and inflammatory mediators / P.M. Ellerbroek, A.M. Walenkamp, A.I. Hoepelman [et al.] // Curr. Med. Chem. – 2004. – Vol. 11. – P.

253-266.

108 Efficacy of voriconazole in a murine model of cryptococcal central nervous system infection / C. Serena, F.J. Pastor, M. Marine [et al.] // Jurnal of antimicrobial chemotherapy. – 2007. – Vol. 60. – P. 162-165.

109 Elevated cerebrospinal fluid pressures in patients with cryptococcal meningitis and acquired immunodeficiency syndrome / D.W. Denning, R.W. Armstrong, B.H. Lewis [et al.] // Am. J. Med. – 1991. – Vol. 91. – P. 267-272.

110 Encapsulation of Cryptococcus neoformans regulates fungicidal activity and the antigen presentation process in human alveolar macrophages / A.Vecchiarelli, D. Pietrella, M. Dottorini [et al.] // Clin. Exp. Immunol. – 1994. – Vol. 98. – P.217-

223.

111 Encapsulation of Cryptococcus neoformans with glucuronoxylomannan inhibits the antigen-presenting capacity of monocytes / C. Retini, A. Vecchiarelli, C. Monari [et al.] // Infect Immun. – 1998. – Vol. 66, № 2. – P. 664-669.

112 Enhanced allergic inflammation and airway responsiveness in rats with chronic Cryptococcus neoformans infection: potential role for fungal pulmonary infection in the pathogenesis of asthma / D.L. Goldman, J. Davis, F. Bommarito [et al.] // J. Infect. Dis. – 2006. – Vol. 193. – P. 1178-1186.

113 Enhanced innate immune responsiveness to pulmonary Cryptococcus neoformans infection is associated with resistance to progressive infection / L. Guillot, S.F. Carroll, R. Homer [et al.] // Infect. Immun. – 2008. – Vol. 76, № 10. – P. 4745-

4756.

114 Epidemiology of opportunistic invasive fungal infections in China: review of literature / L. Yong, C.Min, T.Hartmann [et al.] // Chin. Med. J. – 2013. – Vol. 126,

№2. – P.361-368

115 Estimation of the current global burden of cryptococcal meningitis among persons living with HIV/AIDS / B.J. Park, K.A. Wannemuehler, B.J. Marston [et al.] // AIDS. – 2009. – Vol. 23. – P. 525-530.

116 Evans R.J. Macrophages in the immune response against Cryptococcus / R.J.

Evans, R.C. May // Human Fungal Pathogens. - 2nd edition The Mycota XII O. Kurzai (ed.). – Springer-Verlag Berlin Heidelberg, 2014. – P. 97-108.

117 Expression of cytokines and inducible nitric oxide synthasemrna in the lungs of mice infected with Cryptococcus neoformans: effects of interleukin-12 / K. Kawakami, M. Tohyama, X. Qifeng [et al.] // Infect. Immun. – 1997. – P. 1307-

1312.

118 Firacative, C. MALDI-TOF MS Enables the rapid identification of the major molecular types within the Cryptococcus neoformans / C. gattii species complex [Electronic resource] / C. Firacative, L. Trilles, W. Meyer. – Mode of access: http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0037566

119 First reported case of Cryptococcus gattii in the Southeastern USA: Implications for travel-associated acquisition of an emerging pathogen / E.J. Byrnes 3rd, W. Li, Y. Lewit [et al.] // PLoS ONE. – 2009b. – Vol. 4. – e 5851.

120 Fonseca, А. Cryptococcus Vuillemin (1901) / A. Fonseca, T. Boekhout, J.W. Fell

// The yeasts: a taxonomic study / Kurtzman C.P., Fell J.W., Boekhout T. (eds.) –

Elsevier Science & Technology, Amsterdam, 2011. – Р.1665-1741.

121 Fungal strategies for overcoming host innate immune response / L. Chai, M.

Netea, A. Vonk [et al.] // Medical mycology. – 2009. – Vol. 7. – P. 227-236.

122 Fungicidal activity of five cathelicidin peptides against clinically isolated yeasts / M. Benincasa, M. Scocchi, S. Pacor [et al.] // J. Antimicrob. Chemother. – 2006. – Vol. 58. – P. 950-959.

123 Fungicidal properties of defensin NP-1 and activity against Cryptococcus neoformans in vitro / M.S. Alcouloumre, M.A. Ghannoum, A.S. Ibrahim [et al.] // Antimicrobial agents and chemotherapy. – 1993. – Vol. 37, № 12. – P.2628-2632.

124 Gancedo, C. The importance of a functional trehalose biosynthetic pathway for the life of yeasts and fungi / C. Gancedo, C.L. Flores // FEMS Yeast Res. – 2004. – Vol. 4. – P. 351-359.

125 Gantner, B.N. Dectin-1 mediates macrophage recognition of Candida albicans

yeast but not filaments / B.N. Gantner, R.M. Simmons, D.M. Underhill // EMBO J.

– 2005. – Vol. 24. – P. 1277-1286.

126 Gene expression analysis shows a role for the capsule of Cryptococcus neoformans in preventing dendritic cell activation / P. Lupo, Y.C. Chang, B. Kelsall [et al.] // Abstr. 6th International Conference on Cryptococcus & Cryptococcosis, June 24-28, 2005, Boston, USA. – P. 142.

127 Goldman, D. Pathogenesis of pulmonary Cryptococcus neoformans infection in the rat / D. Goldman, S.C. Lee, A. Casadevall // Infect. Immun. – 1994. – P.

624755-624761.

128 Gordon, S. Alternative activation of macrophages / S. Gordon // Nat. Rev.

Immunol. – 2003. – Vol. 3. – P. 23-35.

129 Guerrero, A. Phenotypic switching in Cryptococcus neoformans contributes to virulence by changing the immunological host response / A. Guerrero, B.C. Fries // Infect Immun. – 2008. – Vol. 76, № 9. – P. 4322-4331.

130 Hardison, S.E. Receptor-ligand interactions / S.E. Hardison, G.D. Brown // Fungal infections. Human Fungal Pathogens. 2nd ed. The Mycota XII / O. Kurzai (ed.). – Springer-Verlag, Berlin Heidelberg, 2014. – P.77-96.

131 Heat killed cells of Cryptococcus neoformans var. grubii induces protective immunity in rats: immunological and histopathological parameters / J.L. Baronetti, L.S. Chiapello, M.P. Aoki [et al.] // Med. Mycol. – 2006. – Vol. 44. – P. 493-504.

132 Heitman, J. Cryptococcus from human to model yeast / Heitman J. [et al.] –

Washington: ASM Press, 2011. – 620 p.

133 Hidden Killers: Human Fungal [Electronic resource] / G.D. Brown, D.W.

Denning, N.A.R.Gow [et al.]. – Mode of access: http://stm.sciencemag.org /content

/4/165/165rv13.full.html.

134 Hogan, L.H. Virulence factors of medically important fungi / L.H. Hogan, B.S.

Klein, S.M. Levitz // Clin. Microbiol. Rev. –1996. – Vol. 9, № 4. – P. 469-488.

135 Hull, C.M. Genetics of Cryptococcus neoformans / C.M. Hull, J. Heitman // Annu. Rev. Genet. – 2002. – Vol. 36. – P. 557-615.

136 Hybrid genotypes in the pathogenic yeast Cryptococcus neoformans / T.

Boekhout, B. Theelen, M. Diaz [et al.] // Microbiology. – 2001. – Vol. 147. – P.

891-907.

137 Identification of App1 as a regulator of phagocytosis and virulence of Cryptococcus neoformans. / C. Luberto, B. Martinez-Marino, D. Taraskiewicz [et al.] // J. Clin. Investig. – 2003. – Vol.112 – P.1080–1094.

138 Ikeda, T. Deactivation of macrophage oxidative burstin vitro by different strains of Histoplasma capsulatum / T. Ikeda, J.R. Little // Mycopathologia. – 1996. – Vol.

132. – P. 133-141.

139 IL-12 and IFN-γ are required for initiating the protective Th1 response to pulmonary cryptococcosis in resistant C.B-17 mice / K.A. Hoag, M.F. Lipscomb, A.A. Izzo [et al.] // Am. J. Respir. Cell Mol. Biol. – 1997. – Vol. 17. – P. 733-739.

140 IL-12 protects mice against pulmonary and disseminated infection caused by Cryptococcus neoformans / K. Kawakami, M. Tohyama, Q. Xie [et al.] // Clin. Exp. Immunol. – 1996. – Vol. 104. – P. 208-214.

141 IL-13 induces disease-promoting type 2 cytokines, alternatively activated macrophages and allergic inflammation during pulmonary infection of mice with Cryptococcus neoformans / U. Muller, W. Stenzel, G. Kohler [et al.] // J. Immunol.

– 2007 – Vol. 179. – P. 5367-5377.

142 IL-17 and Th17 Cells / T. Korn, E. Bettelli, M. Oukka [et al.] // Annu. Rev.

Immunol. – 2009. – Vol. 27. – P. 485-517.

143 IL-17 and therapeutic kynurenines in pathogenic inflammation to fungi / L.

Romani, T. Zelante, A. De Luca [et al.] // J. Immunol. – 2008. – Vol. 180. – P.

5157-5162.

144 IL-17 producing gamma-delta T cells are required for a controlled inflammatory response after bleomycin-induced lung injury / R.K. Braun, C. Ferrick, P. Neubauer [et al.] // Inflammation. – 2008. – Vol. 31. – P. 167-179.

145 IL-17 Stimulates Intraperitoneal Neutrophil Infiltration Through the Release of GRO{alpha} Chemokine from Mesothelial Cells / J. Witowski, K. Pawlaczyk, A. Breborowicz [et al.] // J. Immunol. – 2000. – Vol. 165. – P. 5814-5821.

146 IL-17A inhibits the expansion of IL-17A-producing T cells in mice through “short-loop” inhibition via IL-17 receptor / E. Smith, M.A. Stark, A. Zarbock [et al.] // J. Immunol. – 2008. – Vol. 181. – P. 1357-1364.

147 IL-17-producing alveolar macrophages mediate allergic lung inflammation related to asthma / C. Song, L. Luo, Z. Lei [et al.] // J. Immunol. – 2008. – Vol.

181. – P. 6117-6124.

148 IL-17-producing T cells in lung immunity and inflammation / Nembrini C., Marsland B.J. [et al.] // J. Allergy Clin. Immunol. – 2009. – Vol. 123. – P. 986-994.

149 IL-23 and the Th17 pathway promote inflammation and impair antifungal immune resistance / T. Zelante, A. De Luca, P. Bonifazi [et al.] // Eur. J. Immunol.

– 2007. – Vol. 37. – P. 2695-2706.

150 IL-23 enhances the inflammatory cell response in Cryptococcus neoformans infection and induces a cytokine pattern distinct from IL-12 / M.A. Kleinschek, U. Muller, S.J. Brodie [et al.] // J. Immunol. – 2006. – Vol. 176. – P. 1098-1106.

151 Immune recognition of Candida albicans beta-glucan by dectin-1 / N.A. Gow, M.G. Netea, C.A. Munro [et al.] // J. Infect. Dis. – 2007. – Vol. 196. – P. 1565-

1571.

152 Immune sensing of Candida albicans requires cooperative recognition of mannans and glucans by lectin and Toll-like receptors / Netea M.G., Gow N.A., Munro C.A. [et al.] // J. Clin. Invest. – 2006. – Vol. 116. – P. 1642-1650.

153 Immunology of infections with Cryptococcus neoformans. Chapter 17 / P.

Ellerbroek., A. Vecchiarelli, A. Hoepelman [et al.] // Immunology of fungal infection / Brown G.D., Netea M.G. (eds). – Springer, 2007. – P. 383-407.

154 Impact of mating type, serotype, and ploidy on virulence of Cryptococcus neoformans / Lin X., Nielsen K., Patel S. [et al.] // Infect. Immun. – 2008. – Vol.

76, № 7. – P. 2923-2938.

155 Impairment of alternative macrophage activation delays cutaneous leishmaniasis in nonhealing BALB/c mice / C. Holscher, B. Arendse, A. Schwegmann [et al.] // J. Immunol. – 2006. – Vol. 176. – P. 1115-1121.

156 Increasing in vitro resistance to fluconazole in Cryptococcus neoformans Cambodian isolates: April 2000 to March 2002 / B. Sar, D. Monchy, M. Vann [et al.] // J. Antimicrob. Chemother. – 2004. – Vol. 54. – P. 563-565.

157 Inheritance of immune polarization patterns is linked to resistance versus susceptibility to Cryptococcus neoformans in a mouse model / G.H. Chen, D.A. McNamara, Y. Hernandez [et al.] // Infect. Immun. – 2008. – Vol. 76. – P. 2379-

2391.

158 Insights into the mechanisms of protective immunity against Cryptococcus neoformans infection using a mouse model of pulmonary cryptococcosis [Electronic resource] / K.L. Wozniak, S. Ravi, S. Macias [et al.]. – Mode of access: http://www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0006854

159 Interaction between Cryptococcus neoformans and alveolar macrophages / N.T.

Gross, K. Nessa, P. Camner [et al.] // J. Med.Vet. Mycol. – 1997. – Vol. 35. – P.

263-269.

160 Interdependency of interleukin-10 and interleukin-12 in regulation of T-cell differentiation and effector function of monocytes in response to stimulation with Cryptococcus neoformans / C. Retini, T.R. Kozel, D. Pietrella [et al.] // Infect. Immun. – 2001. – Vol. 69. – P. 6064-6073.

161 Interleukin-17 and lung host defense against Klebsiella pneumoniae infection / P.

Ye, P.B. Garvey, P. Zhang [et al.] // Am. J. Respir. Cell. Mol. Biol. – 2001. – Vol.

25. – P. 335-340.

162 Interleukin-23 (IL-23)-IL-17 cytokine axis in murine Pneumocystis carinii

infection / X.L. Rudner, K.I. Happel, E.A. Young [et al.] // Infect. Immun. – 2007.

– Vol. 75. – P. 3055-3061.

163 Interleukin-4 weakens host resistance to pulmonary and disseminated cryptococcal infection caused by combined treatment with interferon-γ-inducing cytokines / K. Kawakami, M.H. Qureshi, T. Zhang [et al.] // Cell. Immunol. –

1999. – Vol. 197. – P. 55-61.

164 Involvement of CD14, Toll-Like Receptors 2 and 4, and MyD88 in the Host Response to the Fungal Pathogen Cryptococcus neoformans in vivo / LE. Yauch, M.K. Mansour, S. Shoham [et al.] // Infect. Immun. – 2004. – Vol. 72, №. 9. –

5373-5382.

165 Johnston, S.A., Cryptococcus interactions with macrophages: evasion and manipulation of the phagosome by a fungal pathogen / S. A. Johnston, R. C. May // Cell. Microbiol. – 2013. – Vol.15, №3. – P. 403 - 411.

166 Kavanaugh, L.A. Recent evolution of the human pathogen Cryptococcus neoformans by intervarietal transfer of a 14-gene fragment / L.A. Kavanaugh, J.A. Fraser, F.S. Dietrich // Mol. Biol. Evol. – 2006. – Vol. 23, № 10. – P. 1879-1890.

167 Khawcharoenporn, T. Non-neoformans cryptococcal infections: a systematic review / T. Khawcharoenporn, A. Apisarnthanarak, L.M. Mundy // Infection. –

2007. – Vol. 35. – P. 51-58.

168 Kish, D.D. CD8 T cells producing IL-17 and IFN-gamma initiate the innate immune response required for responses to antigen skin challenge / D.D. Kish, X. Li, R.L. Fairchild // J. Immunol. – 2009. – Vol. 182. – P. 5949-5959.

169 Kozel, T. R. Dissociation of a hydrophobic surface fromphagocytosis of encapsulated and non-encapsulated Cryptococcus neoformans / T. R. Kozel // Infect. Immun. – 1983. – Vol. 39. – P. 1214-1219.

170 Kozel, T. R. The capsule of Cryptococcus neoformans passively inhibits phagocytosis of the yeast by macrophages / T. R. Kozel, E. C. Gotschlich // J. Immunol. – 1982. – Vol. 129. – P. 1675-1680.

171 Kozel, T.R. Kinetic analysis of the amplification phase for activation and binding of C3 to encapsulated and nonencapsulated Cryptococcus neoformans / T.R. Kozel, M.A. Wilson, W.H. Welch // Infect. Immun. – 1992. – Vol. 60, №8. – P. 3122-7.

172 Kurtzman, C. The yeasts, a taxonomic study / C. Kurtzman, J.W. Fell, T.

Boekhout (eds). – Elsevier, 2011. – 2354 p.

173 Kwon-Chung K.J. Genetic association of mating types and virulence in Cryptococcus neoformans / K.J. Kwon-Chung, J.C. Edman, B.L.Wickes // Infect. Immun. – 1992. – № 60. – P. 602-605.

174 Kwon-Chung K.J., Boekhout T., Fell J.W., Diaz M. Proposal to conserve the name Cryptococcus gattii against C. hondurianus and C. bacillisporus (Basidiomycota, Hymenomycetes, Tremellomycetidae) // Taxon. – 2002. – Vol.

51, № 4. – P. 804-806.

175 Leibund Gut-Landmann S. Immunity to fungi / S. Leibund Gut-Landmann, M.

Wüthrich, T.M. Hohl // Curr. Opin. Immunol. – 2012. – Vol. 24, №4. – P. 449-58.

176 Lengeler, K. B. Serotype AD strains of Cryptococcus neoformans are diploid or aneuploid and are heterozygous at the mating-type locus / K. B. Lengeler, G. M. Cox, J. Heitman // Infect. Immun. – 2001. – Vol. 69, № 1. – P. 115-122.

177 Levitz, S. M. Cryptococcus: the once-sleeping giant is fully awake / S. M. Levitz, T. Boekhout // FEMS Yeast Res. – 2006. – Vol. 6, № 4. – P. 461-462.

178 Levitz, S.M. Killing of Aspergillus fumigatus spores and Candida albicans yeast phase by the iron-hydrogen peroxide-iodide cytotoxic system: comparison with the myeloperoxidase-hydrogen peroxide-halide system / S.M. Levitz, R.D. Diamond // Infect. Immun. – 1984. – Vol. 43. – P. 1100-1102.

179 Levitz, S.M. The molecular basis for the immunogenicity of Cryptococcus neoformans mannoproteins / S.M. Levitz, C.A. Specht // FEMS Yeast Res. – 2006.

– Vol. 6, № 4. – P. 513-524.

180 Li, S.S. Cryptococcus / S.S. Li, C.H. Mody // Proc. Am. Thorac. Soc. – 2010. – Vol. 7, №3. – P.186-196.

181 Lin, X. The biology of the Cryptococcus neoformans species complex / X. Lin, J.

Heitman // Annu. Rev. Microbiol. – 2006. – Vol. 60. – P. 69-105.

182 Linden, A. Neutrophils, interleukin-17A and lung disease / A. Linden, M. Laan, G.P. Anderson // Eur. Respir.J. – 2005. – Vol. 25. – P. 159-172.

183 Lutsar, I. Voriconazole concentrations in the cerebrospinal fluid and brain tissue of guinea pigs and immunocompromised patients / I. Lutsar, S. Roffey, P. Troke // Clin. Infect. Dis. – 2003. – Vol. 37. – P. 728-732.

184 NADPH oxidase of human dendritic cells: role in Candida albicans killing and regulation by interferons, dectin-1 and CD206 / M. Donini, E. Zenaro, N. Tamassia [et al.] // Eur. J. Immunol. – 2007. – Vol. 37. – P. 1194-1203.

185 Ma, H. Virulence in Cryptococcus species / Ma H., May R.C. // Advances in

Applied Microbiology. – 2009. – Vol.67. – P.131-190.

186 Macrophage-Cryptococcus Interactions: An Update / M.K. Mansour, J.L. Reedy, J.M. Tam [et al.] // Curr. Fungal. Infect. Rep. – 2014. – Vol. 8. – P. 109-115.

187 MALDI Biotyper 3.1. User manual revision 1. Bruker Daltonics. – Bremen. –

2012. – 212 p.

188 Mansour, M.K. Interactions of fungi with phagocytes / Mansour M.K., Levitz

S.M. // Current Opinion in Microbiology. – 2002. – Vol. 5. – P. 359-365.

189 Many globally isolated AD hybrid strains of Cryptococcus neoformans originated in Africa / A. P. Litvintseva, X. Lin, I. Templeton [et al.] // PLoS Pathog. – 2007. – Vol. 3, № 8. – e 114.

190 Martinez, L.R. Cryptococcus neoformans cells in biofilms are less susceptible than planktonic cells to antimicrobial molecules produced by the innate immune system / L.R. Martinez, A. Casadevall // Infect. Immun. – 2006. – Vol. 74. – P.

6118-6123.

191 Martinez, L.R. Cryptococcus neoformans var. neoformans (serotype D) strains are more susceptible to heat than C. neoformans var. grubii (serotype A) strains / L.R. Martinez, J. Garcia-Rivera, A. Casadevall // J. Clin. Microbiol. – 2001. – Vol.

39, № 9. – P. 3365-3367.

192 Matrix-assisted laser desorption ionization – time of flight mass spectrometry- based method for discrimination between molecular types of Cryptococcus

neoformans and Cryptococcus gattii / Posteraro B.,Vella A., Cogliati M. [et al.] // J. Clin. Microbiol. 2012. - Vol. 50, N. 7. –P. 2472 - 2476.

193 McFadden, D.C. The physical properties of the capsular polysaccharides from Cryptococcus neoformans suggest features for capsule construction / D.C. McFadden, M. De Jesus, A. Casadevall // J. Biol. Chem. – 2006. – Vol. 281, № 4.

– P. 1868-1875.

194 McGinness, J. Amorphous semiconductor switching in melanins / J. McGinness, P. Corry, P. Proctor // Science. – 1974. – Vol. 183. – P.853-855.

195 McKenzie, A.N. Interleukin-13: characterization and biologic properties / A.N.

McKenzie, G. Zurawski // Cancer Treat. Res. – 1995. – Vol. 80. – P. 367-378.

196 Medzhitov R. The innate immune system / Medzhitov R. // Fundamental immunology. –Lippincott Wiliams&Wilkins, 2008. – P. 428-450.

197 Melanin as a potential cryptococcal defence against microbicidal proteins / T.L.

Doering, J.D. Nosanchuk, W.K. Roberts [et al.] // Medical Mycology. – 1999. –

Vol. 37 – P.175-181.

198 Menter, J.M. Electron transfer and photoprotective properties of melanins in solution / J.M. Menter, I. Willis // Pigment. Cell. Res. – 1997. – Vol. 10. – P. 214-

217.

199 Migliorini, P. Macrophage NO2 production as a sensitive and rapid assay for the quantation of murine IFN-γ / P. Migliorini, G. Corradin, S.B. Corradin // J. immunol. met. – 1991. – Vol. 139. – P. 107-114.

200 Mills, K.H. Induction, function and regulation of IL-17-producing T cells / K.H.

Mills // Eur. J. Immunol. – 2008. – Vol. 38. – P. 2636-2649.

201 Missall, T.A. Mechanisms of resistance to oxidative and nitrosative stress: implications for fungal survival in mammalian hosts / T.A.Missall, J.K. Lodge, J.E. McEwen //Eukaryotic Cell. – 2004. – Vol. 3, №4. – P. 835-846.

202 Mitchell, T.G. Cryptococcosis in the era of AIDS: 100 years after the discovery of Cryptococcus neoformans / T.G. Mitchell, J.R. Perfect // Clin. Microbiol. Rev. –

1995. – Vol. 8. – P. 515-548.

203 Molecular evidence that the range of the Vancouver Island outbreak of Cryptococcus gattii infection has expanded into the Pacific Northwest in the United States / E.J. Byrnes 3rd, R.J. Bildfell, S.A. Frank [et al.] // J. Infect. Dis. –

2009a. – Vol. 199. – P. 1081-1086.

204 Monari, C. Glucuronoxylomannan exhibits potent immunosuppressive properties

/ C. Monari, F. Bistoni, A. Vecchiarelli // FEMS Yeast Res. – 2006. – Vol. 6, № 4.

– P. 537-542.

205 Multilocus sequence typing reveals three genetic subpopulations of Cryptococcus neoformans var. grubii (serotype A), including a unique population in Botswana / A.P. Litvintseva, R. Thakur, R. Vilgalys [et al.] // Genetics. – 2006. – Vol. 172. – P. 2223-2238.

206 Naslund, P.K. Cryptococcus neoformans fails to induce nitric oxide synthase in primed murine macrophage-like cells / P.K. Naslund, W.C. Miller, D.L. Granger // Infect. Immun. – 1995. – Vol. 63. – P. 1298-1304.

207 Nicola, A.M. Fungal killing by mammalian phagocytic cells / A.M. Nicola, A.

Casadevall, D.L. Goldman // Curr. Opin. Microbiol. – 2008. – Vol. 11. – P. 313-

317.

208 Opsonic Requirements for Dendritic Cell-Mediated Responses to Cryptococcus neoformans / R.M. Kelly, J. Chen, L.E. Yauch [et al.] // Infect. Immun. – 2005. – Vol. 73, №1. – P. 592-598.

209 Organ-dependent variation of capsule thickness in Cryptococcus neoformans during experimental murine infection / J. Rivera, M. Feldmesser, M. Cammer [et al.] // Infect. Immun. – 1998. – Vol. 66. – P. 5027-5030.

210 Peck, A. Precarious balance: Th17 cells in host defense / A. Peck, E.D. Mellins // Infect. Immun. – 2010. – Vol. 78. – P. 32-38.

211 Perfect, J.R. Clinical practice guidelines for the management of cryptococcal disease: 2010 update by the Infectious Diseases Society of America / J.R. Perfect, W.E. Dismukes, F. Dromer [et al.] // Clin. Infect. Dis. – 2010. – Vol. 50, №3 – P.

291-322.

212 Pfaller, М.А. Drug resistance in Cryptococcus epidemiology and molecular mechanisms / М.А. Pfaller, J.K. Lodge, M.A. Ghannoum // CRYPTOCOCCUS from human pathogen to model yeast / J.Heitman, T.R.Kozel, K.J.Kwon-Chung, J.R.Perfect, A.Casadevall (eds). – ASM Press, Washington DC, 2011. – P.203-216.

213 Phagocytic efficacy of macrophage-like cells as a function of cell cycle and Fcgamma receptors (FcgammaR) and complement receptor (CR)3 expression / Y. Luo, E. Cook, B.C. Fries [et al.] // Clin. Exp. Immunol. – 2006. – Vol. 145. – P.

380-387.

214 Phagocytosis and growth inhibition of Cryptococcus neoformans by human alveolar macrophages: effects of HIV-1 infection / C.C. Reardon, S.J. Kim, R.P. Wagner [et al.] // AIDS. – 1996. – Vol. 10. – P. 613-618.

215 Plonka, P.M. Melanin synthesis in microorganisms –biotechnological and medical aspects / P.M. Plonka, M. Grabacka // ABP. – 2006. – Vol. 53, № 3. – P.

429-443.

216 Polacheck, I. The discovery of melanin production in Cryptococcus neoformans and its impact on diagnosis and the study of virulence / I. Polacheck // Zentralbl. Bakteriol. – 1991. – Vol. 276. – P. 120-123.

217 Polarization optical analysis of the surface structures of various fungi / W. Gahrs, Z. Ti gyi, L. Emody [et al.] // Acta Histochem. – 2009. – Vol. 111, № 4. – P. 308-

315.

218 Postsecretory processing generates multiple cathelicidins for enhanced topical antimicrobial defense / M. Murakami, B. Lopez-Garcia, M. Braff [et al.] // J. Immunol. – 2004. – Vol. 172. – P. 3070-3077.

219 Price, M.S. Host defenses against cryptococcosis / M.S. Price, J.R. Perfect // Immunol. Invest. – 2011. – Vol. 40, №7-8. – P. 786-808.

220 Primary dendritic cells phagocytose Cryptococcus neoformans via mannose receptors and Fc-gamma receptor II for presentation to T lymphocytes / R.M. Syme, J.C. Spurrell, E.K. Amankwah [et al.] // Infect. Immun. – 2002. – Vol. 70. – P. 5972-5981.

221 Production of nitric oxide by rat alveolar macrophages stimulated by Cryptococcus neoformans or Aspergillus fumigatus / N.T. Gross, K. Nessa, P. Camner [et al.] // Med. Mycol. – 1999. – Vol. 37. – P. 151-157.

222 Protection Against Cryptococcosis using a Murine Interferon-gamma Producing Cryptococcus neoformans Strain / F.L. Jr Wormley, J.R. Perfect, C. Steele [et al.] // Infect. Immun. – 2007. – Vol. 75. – P. 1453-1462.

223 Protegrins: leukocyte antimicrobial peptides that combine features of corticostatic defensins and tachyplesins / V.N. Kokryakov, S.S. Harvig, E.A Panyutich [et al.] // FEBS Lett. – 1993. – Vol. 327, № 2. – P. 231-326.

224 Pulmonary cryptococcosis in nonimmunocompromised patients / H.F. Nadrous, V.S. Antonios, C.L. Terrell [et al.] // Chest. – 2003. – Vol. 124. – P. 2143-2147.

225 Pulmonary infection with an interferon-producing Cryptococcus neoformans strain results in classical macrophage activation and protection / S.E. Hardison, S. Ravi, K.L. Wozniak [et al.] // The american journal of pathology. – 2010. – Vol.

176, № 2. – P. 774-785.

226 Radial mass density, charge and epitope distribution in the Cryptococcus neoformans capsule / M.E. Maxson, E. Dadachova, A. Casadevall [et al.] // Eukaryot. Cell. – 2007. – Vol. 6, № 1. – P.95-109.

227 Ramirez-Ortiz, Z.G. The role of dendritic cells in the innate recognition of pathogenic fungi (A. fumigatus, C. neoformans and C. albicans) / Z.G. Ramirez- Ortiz, T.K. Means // Virulence. – 2012. - Vol.3, №7. – P.635-646.

228 Rapid identification of Cryptococcus neoformans and Cryptococcus gattii by matrix-assisted laser desorption ionization – time of flight mass spectrometry / L.R. McTaggart, E. Lei, S.E. Richardson [et al.] // J. Clin. Microbiol. 2011. - Vol. 49, N.

8. - pp. 3050 – 3053.

229 Reaction of superoxide anions with melanins: electron spin resonance and spin trapping studies / W. Korytowski, B. Kalyanamaran, I.A. Menon [et al.] // Biochim. Biophys. Acta. – 1986. – Vol. 882. – P. 145-153.

230 Regulation of cryptococcal capsular polysaccharide by iron / S.E. Vartivarian, E.J. Anaissie, R.E. Cowart [et al.] // J. Infect. Dis. – 1993. – Vol. 167. – P. 186-190.

231 Reid, D.M. Pattern recognition: recent insights from Dectin-1 / D.M. Reid, N.A.

Gow, G.D. Brown // Curr Opin Immunol. 2009. – Vol.21, №1. – P.30-37.

232 Relative contributions of myeloperoxidase and NADPH-oxidase to the early host defense against pulmonary infections with Candida albicans and Aspergillus fumigatus / Y. Aratani, F. Kura, H. Watanabe [et al.] // Med. Mycol. – 2002. – Vol.

40. – P. 557-563.

233 Requirement of interleukin-17A for systemic anti-Candida albicans host defense in mice / W. Huang, L. Na, P.L. Fidel [et al.] // J. Infect. Dis. – 2004. – Vol. 190. – P.624-631.

234 Role of extracellular phospholipases and mononuclear phagocytes in dissemination of cryptococcosis in a murine model / R. Santangelo, H. Zoellner, Т. Sorrell [et al.] // Infect. Immun. – 2004. – № 72. – P. 2229-2239.

235 Role of IFN-γ in regulating T2 immunity and the development of alternatively activated macrophages during allergic bronchopulmonary mycosis / S. Arora, Y. Hernandez, J.R. Erb-Downward [et al.] // J. Immunol. – 2005. – Vol. 174. – P.

6346-6356.

236 Role of mannoprotein in induction and regulation of immunity to Cryptococcus neoformans / D. Pietrella, R. Cherniak, C. Strappini [et al.] // Infect. immun. –

2001. –Vol. 69, №5. – P. 2808-2814.

237 Role of the mannose receptor in a murine model of Cryptococcus neoformans

infection / J.M. Dan, R.M. Kelly, C.K. Lee [et al.] // Infect. Immun. – 2008. – Vol.

6. – P. 2362-2367.

238 Role of TNF-alpha in the induction of fungicidal activity of mouse peritoneal exudate cells against Cryptococcus neoformans by IL-12 and IL-18 / K. Kawakami, M.H. Qureshi, Y. Koguchi [et al.] // Cell. Immunol. – 1999. – Vol.

193. – P. 9-16.

239 Role of tumor necrosis factor and gamma interferon in acquired resistance to Cryptococcus neoformans in the central nervous system of mice / K. Aguirre, E.A. Havell, G.W.Gibson [et al.] // Infect. Immun. – 1995. – Vol. 63. – P. 1725-1731.

240 Roles for inositol-phosphorylceramide synthase 1 (IPC1) in pathogenesis of C. neoformans / C. Luberto, D. L. Toffaletti, E. A. Wills [et al.] // Genes Dev. –2001.

– Vol.15 – P.201–212.

241 Romani, L. Immunity to fungal infections / L. Romani // Nat. Rev. Immunol. –

2011. –Vol. 11. – P. 275-288.

242 Rosas, A.L. Melanization affects susceptibility of Cryptococcus neoformans to heat and cold / A.L. Rosas, A. Casadevall // FEMS Microbiol. Lett. – 2003. – Vol.

153. – P. 265-272.

243 Ruane, P.J. Disseminated infection caused by urease-negative Cryptococcus neoformans / P.J. Ruane, L.J. Walker, W.L. George // J. Clin. Microbiol. – 1988. –

№ 26. – P. 2224-2225.

244 Shoham, S. The immune response to fungal infections / Shoham S., Levitz S.M. // Br. J. Haematol. – 2005. – Vol. 129. – P. 569-582.

245 Signaling via interleukin-4 receptor alfa-chain is required for successful vaccination against schistosomiasis in BALB/c mice / A.P. Mountford, K.G. Hogg, P.S. Coulson [et al.] // Infect. Immun. – 2001. – Vol. 69. – P. 228-236.

246 Six monophyletic lineages identified within Cryptococcus neoformans and Cryptococcus gattii by multi-locus sequence typing / M. Bovers, F. Hagen, E.E. Kuramae [et al.] // Fungal Genet. Biol. – 2008. – Vol. 45, № 4. – P. 400-421.

247 Spread of Cryptococcus gattii in British Columbia, Canada, and detection in the Pacific Northwest, USA / L. MacDougall, S.E. Kidd, E. Galanis [et al.] // Emerg. Infect. Dis. – 2007. – Vol. 13. – P. 42-50.

248 Spread of Cryptococcus gattii into Pacific Northwest region of the United States / K. Datta, K.H. Bartlett, R. Baer [et al.] // Emerg. Infect. Dis. – 2009. – Vol. 15. – P.

1185-1191.

249 Strain-dependent production of interleukin-17/interferon-γ and matrixremodeling- associated genes in experimental / Candida albicans keratitis // Y. Zou, H. Zhang, H. Li [et al.] // Mol. Vis. – 2012. – Vol. 18. – P. 1215-1225.

250 Susceptibility to fluconazole of Cryptococcus neoformans isolates from patients in Saint-Petersburg, Russia / T.S. Bogomolova, N.V. Vasilyeva, I.V. Vybornova [et al.] // Mycoses. – 2013. – Vol. 56, Suppl.4. – P. 64.

251 Synthetic melanin supresses production of proinflammatory cytokines / N.

Mohagheghpour, N. Waleh, S.J. Garger [et al.] // Cell Immunol. – 2000. – Vol. 199. –

P. 25-36.

252 Taborda, C.P. CR3 (CD11b/CD18) and CR4 (CD11c/CD18) are involved in complement-independent antibody-mediated phagocytosis of Cryptococcus neoformans / C.P. Taborda, A. Casadevall // Immunity. – 2002. – Vol. 16. – P. 791-

802.

253 Takeda, K. Toll-like receptors / K. Takeda, T. Kaisho, S. Akira // Annu. Rev.

Immunol. – 2003. –Vol. 21. – P. 335-376.

254 Th17 cells and IL-17 receptor signaling are essential for mucosal host defense against oral candidiasis / H.R. Conti, F. Shen, N. Nayyar [et al.] // J. Exp. Med. –

2009. – Vol. 206. – P. 299-311.

255 The capsule of the fungal pathogen Cryptococcus neoformans / Zaragoza O., Rodrigues M.L., De Jesus M. [et al.] // Adv. Appl. Microbiol. – 2009. – Vol. 68. – P.

133-216.

256 The human cathelicidin peptide LL-37 and truncated variants induce segregation of lipids and proteins in the plasma membrane of Candida albicans / A.L. den Hertog, J. van Marle, E.C. Veerman [et al.] // Biol. Chem. – 2006. – Vol. 387. – P. 1495-1502.

257 The induction of inflammation by dectin-1 in vivo is dependent on myeloid cell programming and the progression of phagocytosis / M. Rosas, K. Liddiard, M. Kimberg [et al.] // J. Immunol. – 2008. – Vol. 181. – P. 3549-3557.

258 The presence of capsule in Cryptococcus neoformans influences the gene expression profile in dendritic cells during interaction with the fungus / P. Lupo, Y.C. Chang, B.L. Kelsall [et al.] // Infect. Immun. – 2008. – Vol. 76. – P. 1581-1589.

259 The two faces of interleukin 10 in human infectious diseases / J. L. Mege, S.

Meghari, A. Honstettre [et al.] // Lancet Infect. Dis. – 2006. – Vol.6. – P. 557-569.

260 TLR-2 and IL-17A in chitin-induced macrophage activation and acute inflammation / C. A. Da Silva, D. Hartl, W. Liu [et al.] // J. Immunol. 2008. – Vol.181. – P.4279-4286.

261 Tucker, S. C. Replication of Cryptococcus neoformans in macrophages is accompanied by phagosomal permeabilization and accumulation of vesicles containing polysaccharide in the cytoplasm / S. C. Tucker, A. Casadevall // Proc. Natl. Acad. Sci. USA. – 2002. – Vol. 99. – P. 3165-3170.

262 Urease as a virulence factor in experimental cryptococcosis / G.M. Cox, A.

Casadevall, J.R. Perfect [et al.] // Infect. Immun. –2000. – Vol. 68, № 2. – P. 443-

448.

263 Urease expression by Cryptococcus neoformans promotes microvascular sequestration, thereby enhancing central nervous system invasion / M.A. Olszewski, M.C. Noverr, G.H. Chen [et al.] // Am. J. Pathol. – 2004. – Vol. 164. – P. 1761-1771.

264 Vazquez-Torres, A. Macrophages in resistance to candidiasis / A. Vazquez- Torres, E. Balish // Microbiol. Mol. Biol. Rev. – 1997. – Vol. 61. – P. 170-192.

265 Vieira, O.V. Phagosome maturation: Aging gracefully / O.V. Vieira, R.J.

Botelho, S. Grinstein // Biochem. J. – 2002. – Vol. 366. – P. 689-704.

266 Villar, C.C. Immune defence mechanisms and immunoenhancement strategies in oropharyngeal candidiasis / C.C. Villar, A. Dongari-Bagtzoglou // Expert. Rev. Mol. Med. – 2009. – Vol. 10. – e 29.

267 Voelz, K. Cryptococcal interactions with the host immune system / K. Voelz, R.C. May // Eukaryotic cell. –2010. – Vol. 9, № 6 – Р. 835-846.

268 Voelz, K. Macrophage-Cryptococcus interactions during cryptococcosis / K.

Voelz // PhD Thesis. – 2010. – 220 р.

269 Voriconazole proves effective in long-term treatment of a cerebral cryptococcoma in a chronic nephropathic HIV-negative patient, after fluconazole failure / S. Sabbatani, R. Manfredi, M. Pavon [et al.] // Mycopathologia. – 2004. – Vol. 158. – P. 165-171.

270 Voriconazole treatment for less-common, emerging, or refractory fungal infections / J.R. Perfect, K.A. Marr, T.J. Walsh [et al.] // Clin. Infect. Dis. – 2003. – Vol. 36. – P. 1122-1131.

271 Wang, Y. Cryptococcus neoformans melanin and virulence: mechanism of action

/ Y. Wang, P. Aisen, A. Casadevall // Infect. Immun. – 1995. – Vol. 63. – P. 3131-

3136.

272 Wang, Y. Decreased susceptibility of melanized Cryptococcus neoformans to UV

light / Y. Wang, A. Casadevall // Appl. Environ. Microbiol. – 1994. – Vol. 60. – P.

3864-3866.

273 Wang, Y. Melanin, melanin“ghosts” and melanin composition in Cryptococcus neoformans / Y. Wang, P. Aisen, A. Casadevall // Infect. Immun. – 1996. – Vol.

64. – P. 2420-2424.

274 Wickes, B.L. The role of mating type and morphology in Cryptococcus neoformans pathogenesis / B.L. Wickes // Int. J. Med. Microbiol. – 2002. – № 292.

– P. 313- 329.

275 Williamson, P.R. Laccase and melanin in the pathogenesis of Cryptococcus neoformans / P.R. Williamson // Front. Biosci. – 1997. – Vol. 2. – e 99-107.

276 Willment, J.A. C-type lectin receptors in antifungal immunity / Willment J.A., Brown G.D. // Trends Microbiol. – 2008. – Vol. 16. – P. 27-32.

277 Wormley, F.L. Jr. Immunology of infection caused by Cryptococcus neoformans

/ F.L. Jr. Wormley, J.R. Perfect // Methods in Molecular Medicine. – 2005. –

Vol.118. – P.193-198.

278 Yauch, L.E. Direct inhibition of T-cell responses by the Cryptococcus capsular polysaccharide glucuronoxylomannan [Electronic resource] / L.E. Yauch, J.S. Lam, S.M. Levitz. – Mode of access: http://www.plospathogens.org/article/ info%3Adoi%2F10.1371%2Fjournal.ppat.0020120.

279 Zaragoza, O. Capsule enlargement in Cryptococcus neoformans confers resistance to oxidative stress suggesting a mechanism for intracellular survival / O. Zaragoza, C.J. Chrisman, M.V. Castelli // Cell. Microbiol. – 2008. – Vol. 10, №10.

– P. 2043-2057.

280 Zaragoza, O. Experimental modulation of capsule size in Cryptococcus neoformans / O. Zaragoza, A. Casadevall // Biol. Proced. Online. – 2004. – Vol. 6,

– P. 10-15.

281 Zaragoza, O. Monoclonal antibodies can affect complement deposition on the capsule of the pathogenic fungus Cryptococcus neoformans by both classical pathway activation and steric hindrance / O. Zaragoza, A. Casadevall // Cell. Microbiol. – 2006. – Vol. 8, № 12. – P. 1862-1876.

282 Zaragoza, O. The efficacy of complement-mediated phagocytosis of Cryptococcus neoformans is dependent on the location of C3 in the polysaccharide capsule and involves both direct and indirect C3-mediated interactions / O. Zaragoza, C.P. Taborda, A. Casadevall // Eur. J. Immunol. – 2003. – Vol. 33. – P.

1957-1967.

Работы по теме диссертации:

283 Влияние вориконазола на взаимодействие макрофагов со штаммами Cryptococcus neoformans разной вирулентности / Л.В. Филиппова, Н.В. Васильева, Е.В.Фролова [и др.] // Проблемы медицинской микологии. − 2014.

− Т.16, №2. − С.140.

284 Влияние размера капсулы грибов Cryptococcus neoformans на их взаимодействие с перитонеальными макрофагами / Л.В. Филиппова, Н.В. Васильева, Е.П. Киселева [и др.] // Проблемы медицинской микологии. −

2008. − Т.10, №2. − С.87.

285 Особенности взаимодействия Cryptococcus neoformans разной вирулентности и альвеолярных макрофагов / Н.В. Васильева, А.А. Степанова, Л.В. Филиппова [и др.] // Проблемы медицинской микологии. − 2011. − Т.13,

№4. − С.46-50.

286 Особенности взаимодействия макрофагов с разными по вирулентности штаммами Cryptococcus neoformans / Л.В. Филиппова, Н.В. Васильева, Е.П. Киселева [и др.] // Проблемы медицинской микологии. − 2010. − Т.12, №1. − С.38-41.

287 Особенности взаимодействия разных штаммов Cryptococcus neoformans с макрофагами / Л.В. Филиппова, Н.В. Васильева, Е.П. Киселева [и др.] // Проблемы медицинской микологии. − 2009. − Т.11, №2. − С.120.

288 Особенности спектра цитокинов, продуцируемых макрофагами, при взаимодействии со штаммами Cryptococcus neoformans разной вирулентности in vitro / Л.В. Филиппова, Н.В. Васильева, Е.П. Киселева [и др.] // Проблемы медицинской микологии. − 2011. − Т.13, №2. − С.114.

289 Продукция цитокинов макрофагами при взаимодействии со штаммами Cryptococcus neoformans разной вирулентности in vitro / Л.В. Филиппова, Н.В. Васильева, Е.П. Киселева [и др.] // Проблемы медицинской микологии. −

2011. − Т.13, №3. − С.45-49.

290 Факторы микробоцидности макрофагов по отношению к штаммам Cryptococcus neoformans разной вирулентности / Л.В. Филиппова, Н.В. Васильева, Е.П. Киселева [и др.] // Проблемы медицинской микологии. −

2010. − Т.12, №2. − С.138-139.

291 Филиппова Л.В. Взаимодействие макрофагов со штаммами Cryptococcus neoformans разной вирулентности / Л.В. Филиппова, Н.В.Васильева, Е.П. Киселева // В сб. науч. труд. «По материалам отчетной сессии 2009 года». – СПб., 2009. – С.14-16.

292 Филиппова, Л.В. Cryptococcus neoformans и врожденный иммунитет / Л.В.

Филиппова, Е.В. Фролова // Проблемы медицинской микологии. − 2011. − Т.13, №2. − С.10-19.

293 Филиппова, Л.В. Чувствительность штаммов Cryptococcus neoformans к антимикробным пептидам in vitro / Л.В. Филиппова, Н.В. Васильева, Е.П. Киселева [и др.] // Проблемы медицинской микологии. − 2012.− Т.14, №2. − С. 132.

294 Cryptococcosis in Saint Petersburg, Russia, 1990–2008 / N.V. Vasilyeva, N.N.

Klimko, T.S. Bogomolova, I.A. Bosak, L.V. Filippova // Abstracts of the 17th Congress of the International Society for Human and Animal Mycology, Tokyo, Japan, May 25-29. – 2009. – Р.472.

295 Different virulence Cryptococcus neoformans strains and cytokine production by macrophages in vitro / L.V. Filippova, N.V. Vasilyeva, E.P. Kiseleva [et al.] // Keystone Symposia on Fungal Pathogens: From Basic Biology to Drug Discovery, Santa Fe, New Mexico, USA, January, 15-20. – 2012. – Р.140.

296 Effect of different virulence Cryptococcus neoformans strains on phagocytosis and cytokine production by macrophages in vitro / L.V. Filippova, N.V. Vasilyeva, E.P. Kiseleva [et al.] // Mycoses. – 2011. – Vol.54. – P.115.

297 Fungicidal activity of antimicrobial peptides against Cryptococcus neoformans in vitro / L.V. Filippova, N.V. Vasilyeva, E.P. Kiseleva [et al.] // Mycoses. – 2012. – Vol. 55. – S.4. – P.108.

298 Interactions of murine phagocytes and Cryptococcus neoformans strains in combination with voriconazole / L.V. Filippova, N. V. Vasilyeva, E. V. Frolova [et al.] // Mycoses: Diagnosis. Therapy and prophylaxis of fungal disease. – 2014. – Vol. 57. – S.1. – P.90.

299 The interaction of macrophages with different Cryptococcus neoformans isolates

/ L.V. Filippova, N.V. Vasilyeva, E.P. Kiseleva [et al.] // Mycoses. – 2009. –

Vol.52. – P.91-92.